The Beacon in Deadpool's life, Theresa Rourke has forever been the key to Wade's happiness: She's always been there to ground him in reality and assure him of his sanity and potential for goodness-- hidden though those traits may be. Lately she's had a lot of trouble in her own life, and hasn't had much time to help out poor ol' Deadpool.

 Sandi was Deadpool’s assistant, coordinator and secretary at Deadpool Inc. and now works for Agent X.

Roommate,confidant, and prisioner of Deadpool, this old lady's kindly visage hides a mind that is more than a match for Deadpool's quick wit and biting remarks. Like the
rest of this ingredient group, little about Al's origin is known.		 Powers: increased strength, excellent marksmanship, trained in the use of hand fire weapons and her lasso
This Charming lady has a dark streak that makes Deadpool look like an altar boy,and a rap sheet a mile long. She once served as the Kingpin's personal assassin, but that doesn't mean she's above killing for the fun of it. A real blast at parties, this one! Powers: heightened mimicry ability gives him a photographic memory, allows him to duplicate any voice patterns he's heard, and perfectly duplicate the movements and fighting styles of anyone he observes for more than a few seconds
The Motley group of mercs that make up what's left of Deadpool's "posse"
Hang out at the decrepit old building formerly known as Sister Margret's Home for Wayward Girls--the Hellhouse! Patch(the Hellhouse's dispatcher guy), C.F. (the super-malleable fat guy), and Fenway (the baseball-referencing guy) are three of the lastpeople on the planet who feel any loyalty to Deadpool.		    
Formerly the seeing eye dog of Matt Murdock (Daredevil), Deuce was swindled away from Foggy Nelson by Weasel. Now Deadpool has a pet, and may God have mercy on poor Deuce's canine soul.    
  A product of LL&L's pre-cog department called "Fleshwerks," the once-human being known only as Montgomery has the ability to forecast probabilities and percentages -- specifically those involving LL&L's Mithras Directive. His horrible appearance hides his all-too-human feelimgs and desires, and he has taken a special interest in Zoe and her success with Mithras project.    
  An agent of LL&L, it is Zoe Culloden's responsibility to guide Deadpool and groom him for his role as the modern-day "messiah" the galaxy will soon require. Anyone else would've given up on Wade at this point, but Zoe's belief in Deadpool is unwavering.    
  An agent of LL&L, Noah DuBois is the right-hand man of Overboss Dixon.
Although Noah is technically Zoe's superior, the two treat each other as colleagues,
and Noah has on occasion made Zoe privy to unauthorized information in order to ensure her success with Deadpool. Although he is loyal to a fault, he doesn't entirely trust Dixon's motivations.		    
  Dixon is the head of LL&L's mysterious Mithras Directive. Although little else is known about him,
it is blatantly obvious that he seems almost hopeful that Deadpool will fail in his role in the Directive. Dixon relies on Noah, for support and loyalty.